Though addiction to THC is rare, it can occur in those who use higher THC doses over a long, consistent period. Cannabis dosing and consumption methods play a role in how long it lasts. Edibles are likely to last 6 to 8 hours, while vaporized products last a fraction of that time.

How To Take A Weed Tolerance Break

• Interestingly, certain areas of the body develop tolerance more rapidly than others.
• These can interact with some of the CB2 endocannabinoid receptors that govern inflammation.
• This happens because Tetrahydrocannabinol (THC) — the psychoactive compounds in cannabis — turns on CB1 cannabinoid receptors in the brain.

Over time with very regular use, the doses of THC needed to achieve the same effects can get quite high, which can become costly, what is low tolerance weed time consuming, or both. This translates to the individual deciding if more weed is needed to achieve the desired effects, whether for pain relief or a happy high. However, only abstinence can reveal any symptoms of withdrawal and therefore, dependence. While different, tolerance and dependence can be related, as higher tolerance can be an indicator of the potential for dependence.

How to Manage THC Tolerance

Starting with a smaller amount when trying a new strain is generally recommended. Pay attention to how the new strain makes you feel, both in terms of the high it delivers and any potential side effects. Across the board, fans of the strain report it as efficient in relieving chronic pain, eye pressure, and hypertension. But more than that, they report it as being an all-around manageable good time.

How to Lower Weed Tolerance: Tips for a Tolerance Reset

• Not only will exercise help with metabolizing THC, it will also help improve your mood.
• Therefore, the downregulation of CB1 and CB2 (cannabinoid receptors type 1 and 2) leads to developing cannabis tolerance.
• You see, there are advantages to having low tolerance because you can mature into it with time and experience.

How long this break must be will depend on how developed your tolerance is and how frequently you use cannabis. Heavy users may need the entire four weeks, but more occasional users may only need a week or less. For instance, Sober living house some people may feel anxious, dizzy, or nauseous after using cannabis.

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Some people aim to keep their tolerance low to bring their cannabis spending down, but for others, a lower tolerance increases the chances of experiencing unpleasant side effects. Mice who were given twice daily injections of THC at 10 mg/kg developed tolerance to THC’s pain-relieving and sedative effects after 36 hours (i.e., 3 THC injections). Tolerance to THC’s sedative effects was stronger than to its pain-relieving effects, suggesting that different brain regions or brain cells are more susceptible to tolerance than others. Cannabis has been increasingly recognized for its potential in alleviating anxiety. However, choosing the best weed for anxiety can be challenging due to individual differences in how cannabis affects the body.